Searchable abstracts of presentations at key conferences in endocrinology

ea0034p246 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2014

Impact of chronic heart failure on adipose tissue functional plasticity: a role for fatty acids?

Yale Andrew , Cobb Malcolm , Lyon Alexander , Mostyn Alison

Chronic heart failure (HF) is a major cause of morbidity and mortality in humans and domestic animals. HF is characterised by chronic inflammation and functional changes in non-cardiovascular tissues; obesity is also associated with low level chronic inflammation, with adipose tissue (AT) exhibiting infiltration of macrophages and alterations in fatty acid (FA) profiles. The aim of this project was to investigate expression of regulators of lipid metabolism and inflammation an...